Application of deep eutectic solvents in sample preparation

Abstract

In the chemical analysis process, in order to concentrate the trace analytes in complex samples and remove the matrix interference, sample preparation is necessary. It is vitally important to develop a simple, efficient, rapid and environmentally friendly sample preparation technique. Deep eutectic solvents (DESs) as a kind of emerging green solvent, have unique features such as low volatility, biodegradability, environmental friendliness, low cost and adjustable miscibility compared with the traditional organic solvents. DESs have been widely used in the sample preparation by combining with various extraction techniques such as ultrasound assisted extraction, microwave-assisted extraction, hollow fiber extraction and solid phase extraction. It can not only improve extraction efficiency and reduce the cost of conventional analysis, but also reduce the detrimental impacts on human health and environmental pollution. The present review provides the applications of DESs in the analysis of food, environment, biological samples, natural products and petrochemical industry in recent 5 years.