Abstract
Twenty-five B-cell-depleted patients (24 following anti-CD19/20 therapy) diagnosed with coronavirus disease 2019 had been symptomatic for a median of 26 days but remained antibody negative. All were treated with convalescent plasma with high neutralizing antibody titers. Twenty-one (84%) recovered, indicating the potential therapeutic effects of this therapy in this particular population.
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Gharbharan, A., Geurtsvankessel, C. H., Jordans, C. C. E., Blaauw, M., Van Der Klift, M., Hassing, R. J., … Rijnders, B. J. A. (2022). Effects of Treatment of Coronavirus Disease 2019 with Convalescent Plasma in 25 B-Cell-Depleted Patients. Clinical Infectious Diseases, 74(7), 1271–1274. https://doi.org/10.1093/cid/ciab647
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