Dioxygenation of cysteamine to hypotaurine at a tris(pyrazolyl)borate iron(ii) unit-cysteamine dioxygenase mimicking?

Abstract

A novel complex TpMe,PhFe(SCH2CH2NH2) has been synthesized as a speculative model for ADO. Indeed its reaction with O2 led to the dioxygenation of the S atom and thus to hypotaurine. This finding may allow us to draw conclusions on the constitution of the ADO active site, whose structure is still unknown. This journal is