Synthesis and Reactivity toward Acyl Chlorides and Enones of the New Highly Functionalized Copper Reagents RCu(CN)ZnI

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Abstract

The new and highly functionalized copper reagents RCu(CN)ZnI obtained from readily available primary and secondary alkylzinc iodides by a transmetalation in THF with the soluble salt, CuCN-2LiX, react in good yields with acyl chlorides and enones, respectively, to afford ketones and 1,4-addition products. © 1988, American Chemical Society. All rights reserved.

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Knochel, P., Yeh, M. C. P., Berk, S. C., & Talbert, J. (1988). Synthesis and Reactivity toward Acyl Chlorides and Enones of the New Highly Functionalized Copper Reagents RCu(CN)ZnI. Journal of Organic Chemistry, 53(10), 2390–2392. https://doi.org/10.1021/jo00245a057

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