Abstract
A new aristolactam, named enterocarpam-III (10-amino-2,3,4,6-tetramethoxy phenanthrene-1-carboxylic acid lactam, 1) together with the known alkaloid stigmalactam (2), were isolated from Orophea enterocarpa. Their structures were elucidated on the basis of interpretation of their spectroscopic data. Compounds 1 and 2 exhibited significant cytotoxicities against human colon adenocarcinoma (HCT15) cell line with IC50 values of 1.68 and 1.32 μM, respectively. © 2012 by the authors.
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Nayyatip, S., Thaichana, P., Buayairaksa, M., Tuntiwechapikul, W., Meepowpan, P., Nuntasaen, N., & Pompimon, W. (2012). Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities. International Journal of Molecular Sciences, 13(4), 5010–5018. https://doi.org/10.3390/ijms13045010
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