Analysis of biomarkers in sweat and its comparative study with blood

Abstract

In the current medical field, the many methods used to analyze the bio fluids for biomarkers are blood, urine, saliva and sweat. Blood testing by sampling is to be done frequently for analysis from patients rendering them prone to higher chances of infection and storage for the procedure also proves difficult. Investigations into biomarkers contained in Sweat have so far been limited. Compare to blood, most of the drugs are accumulated in sweat. It is noteworthy that certain biomarkers like nitrogenous compounds, metal and non-metal ions, metabolites and xenobiotics are found in sweat in such the amount approximately equal to other biofluids. In this paper, the sweat collection and its analysis for determining biomarkers are proposed. Additionally, comparison of biomarkers in blood and sweat had done and tried to prove that sweat is noninvasive, cost effective and accurate analysis compared to blood.