Abstract
A novel synthesis of thiazolidine-2-thione and thiazolidin-2-one derivatives is described with the iodo-cyclothiocarbamation reaction as the key step for the heterocyclic ring formation. This new method has been applied to the synthesis of thiazolidinones as bioisosteric analogs of Linezolid 2. Antimicrobial properties of two new thiazole derivatives are reported. © ARKAT.
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Sattigeri, V. J., Soni, A., Singhal, S., Khan, S., Pandya, M., Bhateja, P., … Mehta, A. (2005). Synthesis and antimicrobial activity of novel thiazolidinones. Arkivoc, 2005(2), 46–59. https://doi.org/10.3998/ark.5550190.0006.205
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