LC-MS-MS analysis of N,α-diethylphenethylamine (N,α-ETH) and its positional isomer N,ß-diethylphenethylamine (N,ß-ETH) in dietary supplements

Abstract

In a previous publication, we reported on the analysis of several dietary supplement/exercise formulas and the quantitation of N,α-diethylphe-nethylamine (N,α-ETH, 3). In this article we report on the reanalysis of these products using LC-MS-MS and GC-MS methods capable of clearly separating the N,α-isomer (3) from its N,ß-isomer (N,ß-ETH, 4). The reanalysis, by both methods, showed that all samples previously reported as containing N,α-ETH (3) do contain only that isomer with no detectable concentrations of the N,ß-ETH (4).