Comparison of MR and PET imaging for the evaluation of liver metastases

Abstract

Purpose: To compare the accuracy of fluoro-18-deoxyglucose positron emission tomography (FDG-PET) and dynamic-enhanced magnetic resonance imaging (MRI) scans in the diagnosis of liver metastatic lesions from colon and other sources. Materials and Methods: Thirty consecutive patients with known or suspected metastatic lesions were scanned by both MRI and PET. Histopathology and/or clinical outcome, including cross-sectional imaging follow up, were used as a gold standard. Results: Of 30 patients, 16 were positive by pathology and/or clinical outcome and 14 were negative for liver metastases. The sensitivity, specificity, and positive and negative predictive values on MRI were 85.7%, 100%, 100%, and 89%, respectively, compared to 71%, 93.7%, 90.9%, and 79% on FDG-PET. The difference between the two methods was not significant (X2 = 0.2, P > 0.05). Conclusion: Our study showed no significant difference in detection of liver metastases using MRI or FDG-PET. However, MRI has advantages in spatial resolution and lesion characterization. © 2003 Wiley-Liss, Inc.