Evaluation of renal function in patients with psoriasis using immunobiologicals

Abstract

The aim of this study was to evaluate renal function in patients with psoriasis using immunobiologicals. A prospective study was conducted with 15 patients with confirmed diagnosis of psoriasis who were starting to use immunobiologicals. The mean age was 41±11 years, with 60% females. The mean time of disease was 11±6.6 years. Significant changes in creatinine and creatinine clearance were not observed in the course of the study. There was an increase in transaminases and a decrease in magnesium levels.O objetivo deste estudo é avaliar a função renal de pacientes com psoríase em uso de imunobiológicos. Foi realizado estudo prospectivo com 15 pacientes com diagnóstico confirmado de psoríase, que iniciariam o tratamento com algum imunobiológico. A média de idade foi de 41±11 anos, sendo 60% do sexo feminino. O tempo médio de doença era de 11±6,6 anos. Não foram evidenciadas alterações significativas nos valores de creatinina sérica e/ou do clearance de creatinina durante o estudo. Houve aumento das enzimas hepáticas e redução dos níveis de magnésio.