The strength-interval curve in cardiac tissue

Abstract

The bidomain model describes the electrical properties of cardiac tissue and is often used to simulate the response of the heart to an electric shock. The strength-interval curve summarizes how refractory tissue is excited. This paper analyzes calculations of the strength-interval curve when a stimulus is applied through a unipolar electrode. In particular, the bidomain model is used to clarify why the cathodal and anodal strength-interval curves are different, and what the mechanism of the "dip" in the anodal strength-interval curve is. © 2013 Sunil M. Kandel and Bradley J. Roth.