Mecanismos de resposta imune às infecções

  • Machado P
  • Araújo M
  • Carvalho L
  • et al.
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Abstract

O conhecimento dos principais mecanismos de defesa imune contra os diversos agentes infecciosos permite a compreensão da patogênese das doenças infectoparasitárias e das várias estratégias do hospedeiro e do parasita. O sistema imunológico atua numa rede de cooperação, envolvendo a participação de muitos componentes estruturais, moleculares e celulares. Nesse cenário encontra-se o delicado equilíbrio entre a saúde e a doença, em que tanto a deficiência quanto o exagero resultam em dano tecidual. Este artigo explora esses aspectos e algumas abordagens terapêuticas que surgem desse entendimento.Knowledge acquired about the main immune mechanisms protecting against various infectious agents leads to a better understanding of the pathogenesis of infectious/parasitic diseases and of various strategies specific to the host and parasite. The immune system performs along a cooperation network, which involves the participation of several structural, molecular and cellular components. The fine balance between health and disease is found in this scenario, in which deficiency as much as excess may result in tissue damage. This article explores such aspects and a number of therapies arising from the knowledge acquired.

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APA

Machado, P. R. L., Araújo, M. I. A. S., Carvalho, L., & Carvalho, E. M. (2004). Mecanismos de resposta imune às infecções. Anais Brasileiros de Dermatologia, 79(6), 647–662. https://doi.org/10.1590/s0365-05962004000600002

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