Reliable induction of sleep spindles with intracranial electrical pulse stimulation

3Citations
Citations of this article
19Readers
Mendeley users who have this article in their library.

Abstract

Neocortical sleep spindles have been shown to occur more frequently following a memory task, suggesting that a method to increase spindle activity could improve memory processing. Stimulation of the neocortex can elicit a slow oscillation (SO) and a spindle, but the feasibility of this method to boost SO and spindles over time has not been tested. In rats with implanted neocortical electrodes, stimulation during slow wave sleep significantly increased SO and spindle rates compared to control rest periods before and after the stimulation session. Coordination between hippocampal sharp-wave ripples and spindles also increased. These effects were reproducible across five consecutive days of testing, demonstrating the viability of this method to increase SO and spindles.

Cite

CITATION STYLE

APA

Eckert, M. J., Iyer, K., Euston, D. R., & Tatsuno, M. (2021). Reliable induction of sleep spindles with intracranial electrical pulse stimulation. Learning and Memory, 28(1), 7–11. https://doi.org/10.1101/LM.052464.120

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free