Abstract
In this study, we describe the synthesis of 1,4-disustituted-1,2,3- triazolo-ribonucleosides by means of 1,3-dipolar cycloaddition between various N-1 propargyl-pyrimidines and 1'-azido-2',3',5'-tri-O-benzoylribose catalyzed by Na2CuP2O7/sodium ascorbate. All obtained compounds were evaluated for their anti-HCV activity in vitro. © ARKAT-USA, Inc.
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Elayadi, H., Mesnaoui, M., Korba, B. E., Smietana, M., Vasseur, J. J., Secrist, J. A., & Lazrek, H. B. (2012). Preparation of 1,4-disubstituted-1,2,3-triazolo ribonucleosides by Na 2CuP2O7 catalyzed azide-alkyne 1,3-dipolar cycloaddition. Arkivoc, 2012(8), 76–89. https://doi.org/10.3998/ark.5550190.0013.807
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