Generalisation of the Eyring–Kramers Transition Rate Formula to Irreversible Diffusion Processes

Abstract

In the small noise regime, the average transition time between metastable states of a reversible diffusion process is described at the logarithmic scale by Arrhenius’ law. The Eyring–Kramers formula classically provides a subexponential prefactor to this large deviation estimate. For irreversible diffusion processes, the equivalent of Arrhenius’ law is given by the Freidlin–Wentzell theory. In this paper, we compute the associated prefactor and thereby generalise the Eyring–Kramers formula to irreversible diffusion processes. In our formula, the role of the potential is played by Freidlin–Wentzell’s quasipotential, and a correction depending on the non-Gibbsianness of the system along the minimum action paths is highlighted. Our study assumes some properties for the vector field: (1) attractors are isolated points, (2) the dynamics restricted to basin of attraction boundaries are attracted to single points (which are saddle-points of the vector field). We moreover assume that the minimum action paths that connect attractors to adjacent saddle-points (the instantons) have generic properties that are summarised in the conclusion. At a technical level, our derivation combines an exact computation for the first-order WKB expansion around the instanton and an exact computation of the first-order match asymptotics expansion close to the saddle-point. While the results are exact once a formal expansion is assumed, the validity of these asymptotic expansions remains to be proven.