Prognostic Significance of Electrocardiographic Change during Anginal Attack in Patients with Unstable Angina

Abstract

Objective and Methods We examined the prognostic significance of electrocardiographs change during anginal attack, C-reactive protein and fibrinogen in 169 patients with unstable angina. Results During the 90-day follow-up period, 26 patients (15%) exhibited new cardiac events (death, myocardial infarction or urgent revascularization). Using multivariate analysis, ST depression (relative risk 7.507 [95% confidence intervals 1.842-30.592], p<0.01) during anginal attack was found to be an independent risk factor to predict cardiac events as well as diabetes mellitus, an increased total cholesterol level and the use of a thrombolytic agent. C-reactive protein and fibrinogen did not have prognostic significance. Conclusion ST depression during anginal attack is an independent risk predictor for new cardiac events in patients with unstable angina.