Alopecia universalis during treatment with leflunomide and adalimumab - Case report

Abstract

Alopecia areata is a non-scarring form of alopecia that can be localized or widespread. Its etiology is unknown, but immunological factors are implicated in its pathogenesis. With the more frequent use of anti TNF- α biologic drugs, some alopecia areata cases during their use have been described. We report a case of universal alopecia in a patient with rheumatoid arthritis while using adalimumab and leflunomide. © 2014 by Anais Brasileiros de Dermatologia.