Aterocollagen intracordal injection

Abstract

Aterocollagen is a heteroprotein originated from calf skin. Use of this material in intracordal injections has disadvantages in the form of allergic reaction and a high absorption rate; however, it is easy to handle and is suitable for day surgery applying laryngeal endoscopy under local anesthesia. Given adequate anesthesia of the larynx, this method can be implemented in almost all cases of vocal fold atrophy. The results of aterocollagen intracordal injection are favorable for atrophy with vocal fold paralysis, especially in median vocal fold fixation. For other atrophic changes including the mucosal layer, voice improvement may be less noticeable. Because of the high absorption rate of the material, several aterocollagen injections are necessary inorder to achieve stable effect. Recently, elderly patients are on the increase in our voice clinic. They complain of hoarseness mainly caused by atrophic changes of the vocal folds. To treat cases of this nature, we hope for development of material optimally suitable for intracordal injections as well as wider adoption of this technique to treat these disorders.