EVALUATION OF AUTOGENOUS FRESH DEMINERALIZED TOOTH GRAFT PREPARED AT CHAIRSIDE FOR DENTAL IMPLANT (CLINICAL AND HISTOLOGICAL STUDY)

Abstract

INTRODUCTION: Although, the chemical composition of dentin is similar to bone, extracted teeth are still considered a clinical waste and therefore being discarded. With successful extraction of growth factors and bone morphogenic proteins (BMPs) from mammalian teeth, many researchers have supported development of a bone substitute using tooth-derived substances. OBJECTIVES: To evaluate clinical, radiological and histological efficiency of autogenous fresh demineralized tooth (AFDT) graft prepared at the chairside for alveolar bone grafting in fresh extracted sockets for dental implant surgery MATERIALS AND METHODS: Ten patients requiring tooth extraction and alveolar bone regeneration for dental implant placement were included in the study. Within 45 minutes the extracted teeth were mechanicaly prepared, grinded, sieved, defatted, demineralized and sterilized. In the same setting, the graft material was used to reconstruct defects at the extraction. After 3 months of uninterrupted healing at time of implant placement bone samples were collected for histological analysis. CBCT were taken preoperative, 3months after grafting and 3 and 6 months after implant placement. RESULTS: Histologically the osteoconductive, Osteoinductive and Biodegradation of (AFDT) graft was evident. Clinically 100 % success rate of implants was achieved, with no adverse tissue reaction. CBCT have shown increase of bone density at the graft site and stability of marginal bone level around implants. CONCLUSIONS: (AFDT) graft should be considered as an option given its autogenous origin and favorable clinical, radiographical and histological outcomes when teeth extraction is necessary.