Social-cognitive bias and depressive symptoms in outpatients with bipolar disorder

Abstract

A deficit of social cognition in bipolar disorder has been shown, even when patients are stable. This study compares the attribution of intentions (social-cognitive bias) in a group of 37 outpatients with bipolar disorder with 32 matched control subjects. Bipolar patients scored significantly higher in the Ambiguous Intentions Hostility Questionnaire, showing an angry and intentionality bias (P =.001, P =.02). Differences in blame scale and hostility bias did not reach statistical significance, but a trend was found (P =.06). Bipolar patients with depressive symptoms presented a higher score in the angry bias scale (P =.03) and aggressivity bias scale (P =.004). The global functioning (GAF) correlates significantly with intentionality (P =.005), angry (P =.027), and aggressivity (P =.020) biases. Bipolar patients show a social-cognitive bias that may play a role in their functional outcome. © 2012 Guillermo Lahera et al.