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Synthesis of poison-frog alkaloids 237D, 207A, and two congeners of 235B′ for evaluation to inhibitory effect of nicotinic acetylcholine receptors

Chemical and Pharmaceutical Bulletin (2005) 53(5) 555-560
DOI: 10.1248/cpb.53.555
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Abstract

Enantioselective synthesis of the poison-frog alkaloids 237D, 207A, and two congeners of 235B′ has been achieved. The absolute stereochemistry of 237D was determined to be 5S, 8S, 9R by the present synthesis © 2005 Pharmaceutical Society of Japan.

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Toyooka, N., Kawasaki, M., & Nemoto, H. (2005). Synthesis of poison-frog alkaloids 237D, 207A, and two congeners of 235B′ for evaluation to inhibitory effect of nicotinic acetylcholine receptors. Chemical and Pharmaceutical Bulletin, 53(5), 555–560. https://doi.org/10.1248/cpb.53.555

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