Effect of metiamide on the response to secretin and cholecystokinin in man

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Abstract

The effects of intravenous metiamide on the pancreatic exocrine response to intravenous infusion of secretin plus cholecystokinin was studied in 8 patients with duodenal ulceration. The secretion of bicarbonate and water was not altered by metiamide. The secretion of enzymes was significantly less than control during infusion of metiamide. The differences between the pancreatic and gastric responses to metiamide are discussed.

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Thjodleifsson, B., & Wormsley, K. G. (1975). Effect of metiamide on the response to secretin and cholecystokinin in man. Gut, 16(1), 33–35. https://doi.org/10.1136/gut.16.1.33

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