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Aphidicolin inhibits growth and DNA synthesis in halophilic archaebacteria

Journal of Bacteriology (1984) 159(2) 800-802
DOI: 10.1128/jb.159.2.800-802.1984
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Abstract

Aphidicolin, a specific inhibitor of eucaryotic α DNA polymerase, inhibits the growth of halophilic archaebacteria. In Halobacterium halobium, aphidicolin prevents cell division and DNA synthesis. These results suggest that archaebacterial replicases are of the eucaryotic type.

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Forterre, P., Elie, C., & Kohiyama, M. (1984). Aphidicolin inhibits growth and DNA synthesis in halophilic archaebacteria. Journal of Bacteriology, 159(2), 800–802. https://doi.org/10.1128/jb.159.2.800-802.1984

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