Persistent Diffuse Deep T-Wave Inversion an ECG Manifestation of Myasthenia Gravis in Crisis: A Case Series

Abstract

Myasthenia gravis (MG) is a disorder with specific autoantibodies directed against the nicotinic acetylcholine receptor (AChR) in the neuromuscular junction. Despite the absence of AChR in the cardiac myocytes, cardiac involvement in MG, ranging from asymptomatic electrocardiogram (ECG) changes to fatal tachyarrhythmias, myocarditis, conduction blocks, heart failure and sudden cardiac death, has been documented in a few case reports. In this case series, we report two cases of MG in crisis presenting with deep diffuse persistent T-wave inversions as markers for possible MG-related cardiac disease. KEYWORDS: myasthenia gravis, T-wave inversion, electrocardiographic findings.