Epidemiological characteristic of aphthous stomatitis and real clinical practice of management of patients in Uzbekistan

Abstract

Introduction: The article provides an epidemiological description for patients with chronic recurrent aphthous stomatitis (RAS) and the frequency of their reversal in the general structure of diseases of the oral mucosa from 2014 to 2018. The structure of clinical forms of RAS in the Republic of Uzbekistan (ICD-10) was taken. The study of the dynamics of frequency and debut of various clinical forms of RAS, the gender characteristics of RAS has led to the need for the introduction of modern standards for examination, treatment, and prevention of the disease. The goal of the research is to study the frequency of occurrence of RAS, as well as the real clinical practice of managing patients in the Republic of Uzbekistan and its compliance with existing recommendations. Materials and Method: Patients’ medical records and records of the patients’ consultation journal for five years of work (from 2014 to 2018) were studied. Results: Taking into account the gender and age characteristics of patients with RAS will determine the real clinical picture and prevalence of this disease, increase the ability of monitoring, medical examination and providing timely specialized care, allowing to prevent the progression and maintain the working capacity of patients with this pathology of OCR. Conclusion: The frequency of RAS at the general reception for diseases of OCR is 6.22 ± 0.42%; in the general structure of the disease, the fibrinous form prevails 3.46%; the incidence of necrotic periadenitis is 3.15%; herpetiform aphthous stomatitis is recorded in 2.25% of patients and 1.25%-a symptom in Behcet’s disease. The debut of RAS falls on the age period of 18-34 years (62.50%), which indicates a negative trend of “rejuvenation” of this pathology. For effective treatment and rehabilitation of patients suffering from RAS, it is necessary to conduct a comprehensive examination attracting internists, an appointment of means of immunomodulating therapy and means effectively correcting the most important homeostatic mechanisms in humans.