Action Video Gaming Enhances Brain Structure: Increased Cortical Thickness and White Matter Integrity in Occipital and Parietal Regions

Abstract

Background: Action video games—particularly first-person-shooter (FPS), real-time-strategy (RTS), multiplayer-online-battle-arena (MOBA), and battle-royale (BR) titles—have been linked to enhanced visuospatial skills, yet their impact on brain structure remains unclear. Purpose: To examine, using a cross-sectional design, whether long-term exposure to high-speed genres is associated with variations in cortical thickness and white matter microstructure. Methods: Structural and diffusion MRI were acquired from 27 video-game players (VGPs) and 19 non-video-game players (NVGPs). FreeSurfer-derived cortical thickness and DSI-Studio quantitative anisotropy (QA) were compared between groups, co-varying for intracranial volume. All p-values were Holm–Bonferroni- and FDR-corrected; bootstrap 95% CIs are reported. Results: VGPs showed greater cortical thickness in right inferior and superior parietal, supramarginal, and precuneus cortices (ηp2 = 0.12–0.21) and higher QA along right SOG–SPL and left SOG–IPL tracts. Conclusions: Frequent action gaming is associated with greater cortical thickness in the dorsal stream and enhanced occipito-parietal connectivity. However, causal inference is precluded; longitudinal work is warranted.