OfftargetFinder: A web tool for species-specific RNAi design

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Abstract

Motivation: RNA interference (RNAi) technology is being developed as a weapon for pest insect control. To maximize the specificity that such an approach affords we have developed a bioinformatic web tool that searches the ever-growing arthropod transcriptome databases so that pest-specific RNAi sequences can be identified. This will help technology developers finesse the design of RNAi sequences and suggests which non-target species should be assessed in the risk assessment process.

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Good, R. T., Varghese, T., Golz, J. F., Russell, D. A., Papanicolaou, A., Edwards, O., & Robin, C. (2016). OfftargetFinder: A web tool for species-specific RNAi design. Bioinformatics, 32(8), 1232–1234. https://doi.org/10.1093/bioinformatics/btv747

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