Absence of Interference During High-Multiplicity Infection by Clonally Purified Vesicular Stomatitis Virus

  • Stampfer M
  • Baltimore D
  • Huang A
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Abstract

Stocks of vesicular stomatitis virus free of defective interfering particles were produced by serial clonal isolation. High-multiplicity infections with these stocks led to no interference or formation of defective interfering particles. Defective interfering particles were generated by three successive passages at high multiplicity.

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Stampfer, M., Baltimore, D., & Huang, A. S. (1971). Absence of Interference During High-Multiplicity Infection by Clonally Purified Vesicular Stomatitis Virus. Journal of Virology, 7(3), 409–411. https://doi.org/10.1128/jvi.7.3.409-411.1971

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