The clinical significance of tumor infiltrating lymphoctyes in breast cancer: Does subtype matter?

Abstract

Tumor infiltrating lymphocytes (TILs) are commonly detected in breast tumors but their bearing on disease outcome is uncertain. The importance of TILs appears to be subtype-specific and varies depending on the histologic characteristics of the tumor. As our understanding of tumorigenesis is increasing the relevance of immunobiology will become apparent. © 2012 Krell et al; licensee BioMed Central Ltd.