COVID-19 is a rapidly spreading global threat that has been declared as a pandemic by the WHO. COVID-19 is transmitted via droplets or direct contact and infects the respiratory tract resulting in pneumonia in most of the cases and acute respiratory distress syndrome (ARDS) in about 15 % of the cases. Mortality in COVID-19 patients has been linked to the presence of the so-called “cytokine storm” induced by the virus. Excessive production of proinflammatory cytokines leads to ARDS aggravation and widespread tissue damage resulting in multi-organ failure and death. Targeting cytokines during the management of COVID-19 patients could improve survival rates and reduce mortality.
CITATION STYLE
Ragab, D., Salah Eldin, H., Taeimah, M., Khattab, R., & Salem, R. (2020, June 16). The COVID-19 Cytokine Storm; What We Know So Far. Frontiers in Immunology. Frontiers Media S.A. https://doi.org/10.3389/fimmu.2020.01446
Mendeley helps you to discover research relevant for your work.