The association between stigma and wellbeing in an Italian cohort of PLWH: The role of social support and personal factors

Abstract

Our aim was to assess the association between different types of stigma and physical, behavioural and emotional wellbeing, and to evaluate whether these associations were mediated by the level of social support, age, education, sex and time from HIV diagnosis in an Italian cohort of people living with HIV (PLWH). We enrolled 96 PLWH and had them complete a cross-sectional online survey that included the “HSS-12”, the “SF-12” and the “DASS-21”. We performed linear regression analyses to explore the associations between the HSS-12 scores and cART adherence, viral load, SF-12 and DASS-21 scores, and a mediation analysis to identify mediators in the significant associations. We showed that higher level of depression and worse perception of mental health were significantly associated with higher HSS-12 “personalised stigma” (p =.009, p =.020) “disclosure concerns” (p =.012, p =.039), “concerns about public attitudes” (p =.007, p =.005) and “negative self-image” scores; (p