Age and gender demographic and statistical analysis in oral squamous cell carcinoma in Eastern India

Abstract

Background: Oral squamous cell carcinoma (OSCC) continues to dominate all the oral cancer cases with premalignant disorders, which can also be predictable at the pre-clinical phase of malignancy. Chewing behaviors such as betel quid, areca nut& tobacco are all major risk factors. The majority of OSCC patients present with advanced disease and a poor prognosis. Despite the high prevalence of this cancer, there is a scarcity of rigorous data from Eastern India on its relationship with known risk factors. Objectives: The aim of this study was to evaluate the features at specific ages and gender that could play a major role in the development of oral squamous cell carcinoma. Materials and methods: Demographics and habitual behavior were both subjected to expressive analysis. In patients with oral squamous cell carcinoma, categorical and continuous variables regarding gender were scrutinized. Results: Age with gender cross tabs results reflects the maximum patients 245 (57.24%) were female at the age of 45-64, followed by the same age group male 480 (51.39%). The highest 654 cancer sites were found in the buccal mucosal region, and we found the total number of 349 (53.36%) were in the same age group between 45-64 years. Precisely we got the age mean±SD of 61±9 male and 64±12 female OSSC patients with statistical significance of <0.001 respectively. Conclusion: Finally, the majority of OSCC cases in our area of eastern India were female patients who had been using gudhakhu for a long time and it was found correlating with site of OSCC in female.