The mechanisms underlying cancer dormancy are poorly understood. We have developed a preclinical murine model in which immunosurveillance restrains spontaneous metastases in permanent dormancy. The model faithfully recapitulates human metastatic dormancy and may be useful to decipher the immune mechanisms constraining disease progression, thereby facilitating the development of novel immunotherapeutic approaches to control metastatic disease. © 2014 Landes Bioscience.
CITATION STYLE
Romero, I., Garrido, F., & Garcia-Lora, A. M. (2014). A novel preclinical murine model of immune-mediated metastatic dormancy. OncoImmunology, 3(6). https://doi.org/10.4161/onci.29258
Mendeley helps you to discover research relevant for your work.