Abstract
The latex of Euphorbia nivulia afforded three new ingol diterpenes, 3-acetyl-8-methoxyl-7-angolyl-12-hydroxylingol (7), 3,12-diacetyl-7-hydroxy-8- methoxylingol (8), and 3,12-diacetyl-7-angolyl-8-hydroxylingol (9) along with five known ingol diterpenes 2-6 and a known triterpene cyclonivulinol (1). Their structures were established by means of spectroscopic analysis. Diterpenes 2-9 were evaluated for their cytotoxic activity. © 2003 Pharmaceutical Society of Japan.
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Ravikanth, V., Lakshmi Niranjan Reddy, V., Vijender Reddy, A., Ravinder, K., Prabhakar Rao, T., Siva Ram, T., … Venkateswarlu, Y. (2003). Three new ingol diterpenes from Euphorbia nivulia: Evaluation of cytotoxic activity. Chemical and Pharmaceutical Bulletin, 51(4), 431–434. https://doi.org/10.1248/cpb.51.431
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