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Resistance to HER2-directed antibodies and tyrosine kinase inhibitors

  • Garrett J
  • Arteaga C
Cancer Biology & Therapy (2011) 11(9) 793-800
DOI: 10.4161/cbt.11.9.15045
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Abstract

HER2 (ErbB2) is a member of the ErbB family of transmembrane receptor tyrosine kinases, which also includes the epidermal growth factor receptor (EGFR, ErbB1), HER3 (ErbB3) and HER4 (ErbB4). Bindin...

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Garrett, J. T., & Arteaga, C. L. (2011). Resistance to HER2-directed antibodies and tyrosine kinase inhibitors. Cancer Biology & Therapy, 11(9), 793–800. https://doi.org/10.4161/cbt.11.9.15045

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