Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke (MELAS) syndrome is a progressive multisystemic neurodegenerative disorder. MELAS syndrome impairs oxidative phosphorylation and predisposes patients to lactic acidosis, particularly under metabolic stress. We report 2 siblings with MELAS-associated idiopathic scoliosis who underwent posterior spinal instrumented fusion with measures taken to minimise anaesthetic and surgical stress, blood loss, and operating time.
CITATION STYLE
Loh, K. W., Chan, C. Y. W., Chiu, C. K., Hasan, M. S. B., & Kwan, M. K. (2016). Posterior spinal instrumented fusion for idiopathic scoliosis in patients with multisystemic neurodegenerative disorder: A report of two cases. Journal of Orthopaedic Surgery, 24(2), 273–277. https://doi.org/10.1177/1602400231
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