Massive intestinal ischemia, a rare complication of oral contraceptive-induced mesenteric venous thrombosis: A case report and review of literature

Abstract

Intestinal necrosis and perforation is a clinical and pathological presentation of the infrequently seen mesenteric venous thrombosis in women using oral contraceptives. We report a case of a previously healthy 31-year-old female patient, who presented with a 3-day history of abdominal pain. Although chest and abdomen radiographs showed small bowel obstruction, conservative treatment failed and the patient developed peritonism. Contrast-enhanced Tomography of the abdomen revealed free air associated with dilated and thickened small bowel. A laparotomy was performed and segmental resection of both small and large bowel was required. The pathological examination showed intestinal ischemia and mesenteric venous thrombosis. There were no further predisposing factors and mesenteric venous thrombosis was ascribed to oral contraceptives. © 2009 Efremidou et al; licensee Cases Network Ltd.