Abstract
On the basis of a systematic SAR analysis of substituted quinolines, a derivative 32 was synthesized that shows half-maximal inhibition of the immunostimulatory effect of CpG-oligodeoxynucleotides in vitro at the concentration of 0.24 nM.
Cite
CITATION STYLE
APA
Strekowski, L., Zegrocka, O., Henary, M., Say, M., Mokrosz, M. J., Kotecka, B. M., … Macfarlane, D. E. (1999). Structure-activity relationship analysis of substituted 4- quinolinamines, antagonists of immunostimulatory CpG-oligodeoxynucleotides. Bioorganic and Medicinal Chemistry Letters, 9(13), 1819–1824. https://doi.org/10.1016/S0960-894X(99)00291-7
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
Already have an account? Sign in
Sign up for free