Ohtahara Syndrome: Case Report and Literature Review

Abstract

Ohtahara syndrome or Early Infantile Epileptic Encephalopathiy (EIEE) is a rare form of neonatal epileptic encephalopathy. It has particular electro-clinical, therapeutic and outcome features. Its etiologies remains obscure and are essentially secondary to a congenital or acquired structural malformation of cortical development. We report a case of a term newborn presented with seizures on week two of live. Seizures were intractable. Metabolic workup for seizures was normal. Brain MRI did not reveal any structural abnormality. Electroencephalogram showed suppression pattern suggestive of ohtahara syndrome.