Abstract
A novel alkylated piperazine (3α,5α-diisobutyryl-6α-isopropyl-piperazine-2-one, 1) has been isolated from the n-butanol soluble part of the leaves extract of Arum palaestinum Boiss., the chemical structure and the relative stereochemistry of 1 were elucidated on the basis of 1D and 2D NMR spectroscopic data. Piperazirum showed a significant cytotoxicity against cultured tumor cell lines in vitro. © 2007.
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El-Desouky, S. K., Ryu, S. Y., & Kim, Y. K. (2007). Piperazirum, a novel bioactive alkaloid from Arum palaestinum Boiss. Tetrahedron Letters, 48(23), 4015–4017. https://doi.org/10.1016/j.tetlet.2007.04.032
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