Secondary metabolite analysis and anti-bacterial and fungal activities of marine sponge methanol extract based on coral cover

Abstract

Conservation of coral reefs and marine life is important to maintain population and biodiversity. The aim of the study was to determine the relationship between the inhibition of sponge extract on the growth of bacteria and fungi to analyze the relationship formation of bioactive metabolic substances produced by sponges and their relationship with coral cover conditions.Methods of coral cover observation, habitat analysis and secondary metabolite content, anti-bacterial and fungal activity tests and sponge methanol extract. Results: Three types of sponges, each Clathria reinwardri (CR) lived on medium coral reef cover, live coral and partly on the abiotic component. Hyrtios erectus (HE) and Callyspongia aeresuza (CA) were obtained from damaged coral cover, some sandy live coral and abiotic components.Inhibition of CR > CA > HE sponge methanol extract against the growth of fungi and bacteria. The inhibition of sponge methanol extract against the growth of Escherichia coli (EC) and Staphylococcus aureus (SA) and Malassezia furfur (MF) fungi was the largest by CR sponge methanol extract, but did not have inhibitory activity against Candida albicans (CA). The growth and characterization of the metabolites produced by sponges are influenced by the environmental conditions of coral reef growth and cover.