A 15-month-old male beagle dog used in a toxicity study had a primary renal mesenchymal tumor. Macroscopically, the tumor was a gray-white mass which was found in the right kidney, and extended from the capsule to a position slightly compressing the medulla. Microscopically, most of the tumor cells showed a myxoid pattern, in which the matrix was positive for alcian blue staining. In the other parts of the tumor, a fascicular and wavy pattern was observed, and the matrix was full of collagen fibrils. Immunohis-tochemically, tumor cells were positive for vimentin and fibronectin, and negative for cytokeratin, desmin, α-smooth muscle action, Von Willebrand factor, cyclooxigenase-2 and myelin basic protein. As a result, we diagnosed this case to be a renal mesenchymal tumor. Based on the microscopic findings, interstitial characteristics and immunohistochemical features, the present case was classified as a congenital mesoblastic tumor. © 2012 TheJapanese Society of Veterinary Science.
CITATION STYLE
Suzuki, Y., Takaba, K., Yamaguchi, I., Myoujou, K., Kimoto, N., Ikegami, H., … Takada, C. (2012, February 1). Histopathological, immunohistochemical and ultrastructural studies of a renal mesenchymal tumor in a young beagle dog. Journal of Veterinary Medical Science. https://doi.org/10.1292/jvms.10-0504
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