Iron(III) tosylate-catalyzed deprotection of aromatic acetals in water

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Abstract

The deprotection of aromatic as well as conjugated acetals and ketals in water is catalyzed by iron(III) tosylate (1.0-5.0 mol %). Iron(III) tosylate is an inexpensive and readily available catalyst. The use of water, the most environmentally benign solvent, makes this procedure especially attractive for acetal deprotection. © 2010.

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Olson, M. E., Carolan, J. P., Chiodo, M. V., Lazzara, P. R., & Mohan, R. S. (2010). Iron(III) tosylate-catalyzed deprotection of aromatic acetals in water. Tetrahedron Letters, 51(30), 3969–3971. https://doi.org/10.1016/j.tetlet.2010.05.112

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