Journal ArticleOPEN ACCESS

IP-10/CXCL10 attracts regulatory T cells: Implication for pancreatic cancer

OncoImmunology (2015) 4(9) 1-3
DOI: 10.1080/2162402X.2015.1027473
85Citations
Citations of this article
77Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Pancreatic stellate cells (PSCs) are key components of pancreatic ductal adenocarcinoma (PDAC). We recently demonstrated that IP-10/CXCL10 is highly expressed by PSCs in the presence of pancreatic cancer cells (PCCs) and its expression correlates with infiltration by regulatory T cells (Tregs) and poor survival. Thus, stromal cells in pancreatic cancer can promote immunosuppression and tumor progression, through the expression of IP-10.

Author supplied keywords

Cite

CITATION STYLE

APA

Lunardi, S., Lim, S. Y., Muschel, R. J., & Brunner, T. B. (2015). IP-10/CXCL10 attracts regulatory T cells: Implication for pancreatic cancer. OncoImmunology, 4(9), 1–3. https://doi.org/10.1080/2162402X.2015.1027473

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free