Clotting and cancer progression: platelets count

  • Bromberg M
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Abstract

In knockout mice models of metastasis, platelets, activation of platelet protease-activated receptor 4 (PAR4), and fibrinogen/fibrin formation play key roles in the blood-borne metastasis of tumor cells with procoagulant activity, whereas activation of endothelial cell PAR1 and PAR2 does not appear

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Bromberg, M. E. (2004). Clotting and cancer progression: platelets count. Blood, 104(2), 300–300. https://doi.org/10.1182/blood-2004-05-1815

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