Anti-diarrhoeal activity of the methanolic leaf extract of Phyllanthus muellerianus

Abstract

The methanolic leaf extract of Phyllanthus muellerianus was investigated for anti-diarrhoeal activity. The anti-diarrhoeal activities were investigated using the castor oil-induced diarrhoea, magnesium sulphateinduced diarrhoea, small intestinal and distal colonic propulsion, isolated rabbit jejunum and castor oil-induced intestinal fluid accumulation. The results revealed that the methanolic leaf extract of Phyllanthus muellerianus significantly (p © 2009 International Formulae Group. All rights reserved. Key words: Phyllanthus muellerianus, Euphobiaceae, Herbal medicine, Anti-diarrhoea.