0394 Efficacy of Cognitive Behavioral Therapy for Insomnia on Post-Menopausal Quality of Life

Abstract

Introduction: Insomnia occurs in more than 50% of post-menopausal women, is among the most distressing and debilitating symptoms, and adversely affects quality of life. In a randomized controlled trial, we compared the efficacy of multi-component Cognitive Behavioral Therapy for Insomnia (CBT-I) to a behavioral only insomnia therapy (Sleep Restriction Therapy, SRT) and to a Sleep Education control (SE) for improving quality of life symptoms at post-treatment and 6-month follow-up. Methods: Post-menopausal women (n=117, mean age 56.4 + 5.2 years, 44.4% African American) meeting Research Diagnostic Criteria for insomnia that was temporally associated with menopause were recruited. Participants underwent two nights of PSG to screen for other sleep disorders and to verify an average wake after sleep onset of >; 45 minutes. Eligible participants were randomized to one of three treatment conditions: 6-session CBT-I (n=38), 2-session SRT (n=36), or 6-session SE (n=43). Participants completed the Menopause-Specific Quality of Life (MENQOL) questionnaire before and after treatment and at 6-month follow-up. Results: Linear mixed models showed an overall Condition by Time interaction for the Physical subscale of the MENQOL (F=3.3, p <002), and Psychosocial (p