Terminalia chebula: A treatment against pathogenic proteus vulgaris strains associated with urinary tract infection

Abstract

Terminalia chebula was used to find out the new sort of treatment for the urinary tract infections caused by Proteus vulgaris. The causative agent was identified as Proteus vulgaris by staining and biochemical methods. It is responsible to cause urinary tract infection and most of strains show the resistance against the broad spectrum antibiotics: Ceftazidime (30μg), Ofloxacin (50μg), Norfloxacin (30μg), Tetracycline (30μg), Ampicillin (30μg), Chloramphenicol (25μg) and Gentamycin (20μg). The preparation of seed powders and antibacterial activity of Terminalia chebula was carried out. The acetone and ethanol fruits extracts of Terminalia chebula showed good antibacterial activities and killed the resistant urinary tract associated pathogens of Proteus vulgaris strains. The ethanol extracts of fruit Terminalia chebula showed the superior antibacterial activity than the acetone extracts of Terminalia chebula. The minimal inhibitory concentrations of acetone and ethanol extracts of Terminalia chebula were effective to inhibit the urinary tract pathogenic Proteus vulgaris strains at low concentration. Thus Terminalia chebula fruit can be used as medicinal important fruit to overcome the urinary tract diseases.