Telomere-mediated effects on melanogenesis and skin aging

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Abstract

UV-induced melanogenesis (tanning) and "premature aging" or photoaging result in large part from DNA damage. This article reviews data tying both phenomena to telomere-based DNA damage signaling and develops a conceptual framework in which both responses may be understood as cancer-avoidance protective mechanisms. © 2009 The Society for Investigative Dermatology.

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Gilchrest, B. A., Eller, M. S., & Yaar, M. (2009). Telomere-mediated effects on melanogenesis and skin aging. In Journal of Investigative Dermatology Symposium Proceedings (Vol. 14, pp. 25–31). Nature Publishing Group. https://doi.org/10.1038/jidsymp.2009.9

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