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Synthesis and properties of a novel 2',4'-BNA bearing a urea bridged structure.

Nucleic acids symposium series (2004) (2009) (53) 11-12
DOI: 10.1093/nass/nrp006
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Abstract

Three kinds of novel bridged nucleic acid (BNA) monomers bearing carbamate or urea bridged structures, were designed and synthesized. One of these monomers, a urea-type BNA monomer was successfully incorporated into oligodeoxynucleotides (ODNs), and properties of the ODNs were evaluated. The ODNs containing the urea-type BNA monomers showed RNA selective hybridizing profiles and significant enzymatic stability.

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APA

Yahara, A., Nishida, M., Baba, T., Kodama, T., Imanishi, T., & Obika, S. (2009). Synthesis and properties of a novel 2’,4’-BNA bearing a urea bridged structure. Nucleic Acids Symposium Series (2004), (53), 11–12. https://doi.org/10.1093/nass/nrp006

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